A Guide to Pharmaceutical Particulate Science by Anthony J. Hickey, Timothy M. Crowder, Margaret D. Louey,

By Anthony J. Hickey, Timothy M. Crowder, Margaret D. Louey, Norman Orr

Exploring the expansion in wisdom of particle houses and the range of technological advances in particle manufacture, this ebook supplies readers the instruments they should comprehend particulate technology and its use within the undefined. The authors hide particulate fabric, its shape and construction, sampling from our bodies of powder, particle dimension descriptors and information, habit of debris, instrumental research, particle dimension size and synergy of followed ideas, actual habit of a powder, and in vitro and in vivo functionality standards. They draw the parts of particulate technology right into a unmarried concise description in their integration within the context of product improvement.

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Staniforth, J. N. 1996. Improvements in dry powder inhaler performance: Surface passivation effects. Drug Deliv. Lungs 7: 86–89. Staniforth, J. , and J. E. Rees. 1982a. Effect of vibration time, frequency and acceleration on drug content uniformity. J. Pharmacy Pharmacol. 34:700–706. Staniforth, J. , and J. E. Rees. 1982b. Electrostatic charge interactions in ordered powder mixes. J. Pharmacy Pharmacol. 34:69–76. Staniforth, J. , and J. E. Rees. 1983. Segregation of vibrated powder mixes containing different concentrations of fine potassium chloride and tablet excipients.

Yip, C. , and J. A. Hersey. 1977. Ordered or random mixing: Choice of system and mixer. Drug Dev. Ind. Pharmacy 3:429–438. ©2003 by Interpharm/CRC Press LLC  References 231 Zeng, X. , G. P. Martin, and C. Marriot. 1995. The controlled delivery of drugs to the lungs. Int. J. Pharm. 124:149–164. Zeng, X. , G. P. -K. Tee, and C. Marriott. 1998. The role of fine particle lactose on the dispersion and deaggregation of salbutamol sulphate in an air stream in vitro. Int. J. Pharm. 176:99–110. Zeng, X.

Space Lattices Hooke and Haüy concluded that all crystals were built up of a large number of minute units, each shaped like the larger crystal. Consequently, a space lattice is a regular arrangement of points in three dimensions. 2. Although these are the basic lattices, interpenetration can occur in actual crystals; this interpenetration can potentially give rise to 230 possible combinations. An alternative Bravais-DonnayHarker principle considers space groups rather than lattice types. Generally, crystals cleave along lattice planes.

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